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Phase II Trial of neoadjuvant chemotherapy with docetaxel, cisplatin and 5-FU for advanced esophageal cancer

Phase 2
Recruiting
Conditions
esophageal cancer
Registration Number
JPRN-UMIN000007408
Lead Sponsor
Second Department of Surgery, Wakayama Medical University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
40
Inclusion Criteria

Not provided

Exclusion Criteria

Different histological type from squamous cell carcinoma or adenocarcinoma Patient with allergic response to anticancer drugs (docetaxel, cisplatin, 5-FU) Active or uncontrolled infection Pregnancy (women of childbearing potential: refusal or inability to use effective means of contraception) Clinically significant heart disease Patients with a history of myocardial infarction within the previous three months Patients with uncontrolled diabetes mellitus or hypertension Patients with interstitial pneumonia or pulmonary fibrosis Patients who receive hemodialysis Presence of clinically apparent central nervous system metastases Patients with any other severe concurrent disease, which in the judgment of the investigator, would make the patient inappropriate for entry into this study Decision of unsuitableness by principal investigator or physician-in-charge

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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