JPRN-UMIN000006208
Recruiting
Phase 1
Phase I/II trial of neoadjuvant chemotherapy with UFT/Leucovorin and Irinotecan plus radiation in patients with locally advanced rectal cancer. - Phase I/II trial of neoadjuvant chemotherapy with UFT/Leucovorin and Irinotecan plus radiation in patients with locally advanced rectal cancer.
The University of Tokyo Hospital. Department of surgical oncology.0 sites39 target enrollmentAugust 22, 2011
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- ocally advanced rectal cancer with preoperative diagnosis of T3-4 and N0-3.
- Sponsor
- The University of Tokyo Hospital. Department of surgical oncology.
- Enrollment
- 39
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1\.Allergic to a drug 2\.Contraindications to UFT, Leucovorin and Irinotecan 3\.Active infection 4\.UGT1A: \*6/\*6, \*28/\*28 and \*6/\*28 5\.Severe complications such as ileus, interstitial pneumonia, DM, heart failure, lung failure and liver failure 6\.Pregnant or planning to get pregnant.
Outcomes
Primary Outcomes
Not specified
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