Pilot study on conditioning cortisol levels and its psychophysiological effects

Completed

• Conditions: Op dit moment wordt het onderzoek bij gezonde proefpersonen uitgevoerd. Uitkomsten uit deze lijn van onderzoek bieden in de toekomst mogelijk nieuwe handvatten voor verklaringsmodellen en therapeutische interventies voor aandoeningen waarbij een verstoring in de functie van de HPA-as optreedt.; Niet van toepassing

• Registration Number: NL-OMON37492
• Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

healthy, female, premenopausal, 18 - 45 years of age

Exclusion Criteria

Severe psychiatric and/or somatic diseases, symptoms of infection, use of medication (including oral contraceptives), recent stressful life event

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters of the pilot study are the feasibility of the design<br /><br>(e.g., most useful assessment points for the psychophysiological assessments,<br /><br>safety, drop-out). Variance of endogenous cortisol levels at the evocation<br /><br>phase as well as correlations between cortisol levels at the evocation phase<br /><br>and at baseline in the experimental group will also be assessed, in order to<br /><br>enable a founded power analysis for the main study. In the main study, the main<br /><br>study parameters will be endogenous cortisol levels and psychophysiological<br /><br>parameters (e.g., in response to cognitive and psychosocial tasks) at the<br /><br>evocation phase. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable</p><br>