Back Pain - Linking Phenotype to Pain Mechanism and Outcome.
Recruiting
- Conditions
- Low Back Pain
- Interventions
- Other: no intervention, observational
- Registration Number
- NCT04433299
- Lead Sponsor
- Balgrist University Hospital
- Brief Summary
To investigate whether different clinical, psychophysical and neurophysiological phenotypes can be identified among low back pain patients
- Detailed Description
Low back pain patients will fill in a detailed questionnaire (incl. pain drawing) about their pain. Some of them will undergo a standardized quantitative sensory testing protocol and an fMRI procedure.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
-primary complaint: low back pain clinically not attributable to red flags
Exclusion Criteria
- any major medical or psychiatric condition that affects pain sensitivity
- contraindications to MRI
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description low back pain patients no intervention, observational no intervention controls no intervention, observational no intervention
- Primary Outcome Measures
Name Time Method measures for central sensitization baseline temporal summation and conditioned pain modulation
spatial pain extent baseline spatial pain extent (body map)
- Secondary Outcome Measures
Name Time Method changes in measures for central sensitization changes from baseline to 3 months changes in temporal summation and conditioned pain modulation
changes in spatial pain extent changes from baseline to 3 months changes in spatial pain extent (bodymap)
Trial Locations
- Locations (1)
Balgrist University Hospital
🇨🇭Zürich, Zurich, Switzerland