Comparison of Spinal Kinematics Between Asymptomatic Subjects and Patients With Low Back Pain

Completed

• Conditions: Low Back Pain

• Registration Number: NCT02278549
• Lead Sponsor: Haute Ecole de Santé Vaud

Brief Summary

Low back pain (LBP) is a complex and common problem with major societal repercussions. Clinical evaluations, and especially functional assessments, are necessary for proper diagnosis and decisions on the most appropriate treatment. The assessment of lumbar kinematics has been frequently described. For instance, measures of range of motion (ROM), angular velocities and acceleration of the total lumbar spine (TLx) have demonstrated some differences between healthy subjects and LBP patients. However, recent evidence has suggested that models evaluating the TLx are insufficient. In fact, regional differences in kinematics have been described between the upper lumbar spine and the lower lumbar spine.

The aim of this study is to evaluate the differences in spinal kinematics between healthy subjects and LBP patients using a multi-segment model of the spine that allows regional analysis.

Detailed Description

A case-controlled study will be performed to compare asymptomatics subjects and patients with low back pain. ROM, angular velocities and coordination of the spine will be collected in a laboratory with a camera-based system (VICON). Subjects will have to perform normal ROM assessment in the three anatomical planes, as well as different functional activities such as sit to stand, step and walking. The measurement session will occur on one occasion for each participant.

Study Timeline

• Study First Submitted: 2014-10-27
• Study First Submitted QC: 2014-10-28
• Study First Posted: 2014-10-30
• Study Start: 2014-11
• Primary Completion: 2015-06
• Study Completion: 2015-06
• Status Verified: 2015-10
• Last Update Submitted: 2015-10-26
• Last Update Posted: 2015-10-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

• Sufficient French level
• BMI between 18 and 27
• Non-specific low back pain for more than 3 months (pain provoked by movements, postures or activities)

Exclusion Criteria

• Pregnancy
• Spondylolisthesis
• Infection
• Rheumatological or neurological diseases
• Spinal fractures
• Known spinal deformation (scoliosis, ...)
• Back surgery
• Tumours
• Radicular symptoms (with neurological signs). Pain irradiating in the lower limbs with decrease strength, sensitivity and reflex.
• High level of pain (severity and irritability) at the time of experiment that prevents repeated movements.
• Other concomitant pain or condition that could compromise the evaluation of lumbar kinematics.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Spinal kinematics	Participants will be measured once	kinematics of the spine and pelvis will be measured with a camera-based system. Markers will be placed to have different segments of the spine (lower lumbar spine, upper lumbar spine, lower thoracic spine, upper thoracic spine). Variables such as range of motion, angular velocities or coordination (among others) will be measured.

Secondary Outcome Measures

Name	Time	Method
Score of disability	Participants will be measured once	Oswestry Disability Index. Outcome used primarily for description of the population and correlational analysis
Score of kinesophobia	Participants will be measured once	Tampa Scale of kinesophobia. Outcome used primarily for description of the population and correlational analysis
Score of risk of poor outcomes	Participants will be measured once	Start Back Tool. Outcome used primarily for description of the population and correlational analysis
Pain intensity	Participants will be measured once	Numeric Pain Rating Scale (NPRS). Outcome used primarily for description of the population and correlational analysis

Trial Locations

Locations (1)

University of Lausanne Hospitals; 🇨🇭 Lausanne, Vaud, Switzerland