Outcomes of Biological Therapy on Rheumatoid Arthritis

• Conditions: Rheumatoid Arthritis
• Interventions: Drug: Biological Drug

• Registration Number: NCT05267431
• Lead Sponsor: Sohag University

Brief Summary

Evaluate effect of biological therapy on activity of RA compared to usual DMARDs

Detailed Description

Comparison between RA activity in both groups who recieved biological and DMARDS therapy

Study Timeline

• Status Verified: 2022-02
• Study First Submitted: 2022-02-14
• Study First Submitted QC: 2022-02-23
• Study First Posted: 2022-03-04
• Last Update Submitted: 2022-03-04
• Last Update Posted: 2022-03-21
• Study Start: 2022-06
• Primary Completion: 2023-05
• Study Completion: 2023-10

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• RA patients

Exclusion Criteria

• any other connective tissue disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
RA patients recieved different DMARDS	Biological Drug	RA patients recieved different DMARDS

Primary Outcome Measures

Name	Time	Method
Change in activity of rheumatoid arthritis	After 3 months of treatment	By DAS 28; it include 28 tender and swollen joints, laboratory test (ESR) and visual analogue score, if it higher than 5.1 it mean high disease activity and if lower than 3.2 it mean low activity and consider remission if lower than 2.6

Secondary Outcome Measures

Name	Time	Method
Activity of RA	3 months after treatment	MHAQ.scores include questionnaire from eight activities of daily living and range from 0 to 3 and lower scores mean better function state and high scores mean worse function state

Trial Locations

Locations (1)

Sohag faculty of medicine; 🇪🇬 Sohag, سوهاج, Egypt