Comparing fluid therapy for kidney transplant surgery guided by PVI (Plethysmography Variability Index) monitoring and conventional fluid therapy in improving transplant kidney functio

Not Applicable

• Conditions: End Stage Renal Failure.; End stage kidney disease on dialysis

• Registration Number: IRCT2016072929116N1
• Lead Sponsor: Vice Chancellor for research of Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Kidney transplant recipients between 18 and 70 years old who are not cases of known cardiomyopathy; AF rhythm; Blood tranfusion during surgery; History of valve replacement surgery; History of asthma or chronic obstructive pulmonary disease; Morbid obesity; EF<40%, Hb<7; Symptomatic coronary artery diseasse; Prior kidney transplantation history;

Exclusion criteria: peri-operative arrhythmias; peri-operative blood loss more than 1000cc;

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
rine Volume. Timepoint: Before and after aortic declamping, 2hours after surgery, The day after surgery, 6 months after surgery. Method of measurement: Reading the Urine bag value.;Serum Lactate. Timepoint: Before and after aortic declamping, 2hours after surgery, The day after surgery, 6 months after surgery. Method of measurement: Arterial Blood Gas sample.

Secondary Outcome Measures

Name	Time	Method
Serum creatine. Timepoint: before surgery, The day after surgery. Method of measurement: Biochemistry Lab test.;Blood Urea Nitrogen. Timepoint: before surgery, The day after surgery. Method of measurement: Biochemistry Lab test.;Arterial Blood Gas (ABG). Timepoint: before surgery, before and after aortic declamp, 2hours after surgery, The day after surgery. Method of measurement: Arterial Blood Gas sampling.;Heart Rate per minute. Timepoint: before surgery, before and after aortic declamp, 2hours after surgery, The day after surgery. Method of measurement: Pulse oximetry.;Blood Pressure (Mean Arterial Pressure). Timepoint: before surgery, before and after aortic declamp, 2hours after surgery, The day after surgery. Method of measurement: Non Invasive Blood Pressure monitoring.