Effect of Atorvastatin Usage on Oxidative stress-related Marker Superoxide dismutase and Angiogenesis Factors in the Saliva of Patients with Oral squamous cell carcinoma: A Randomized Clinical Trial

Karaj University of Medical Sciences0 个研究点目标入组 30 人开始时间: 待定最近更新: 2024年7月22日

适应症

试验速览

暂无简介。

•Patients with oral squamous cell carcinoma
•Lack of any other cancer except for oral squamous cell carcinoma
•Not using any medication other than the ones prescribed by the surgeon
•No drug interaction with atorvastatin if taken concurrently with another medication
•Biopsy result of the patient indicates squamous cell carcinoma of the oral mucosa
•Having similar histopathology grades
•Ability to personally provide written informed consent or to understand and collaborate throughout the study

•Inability or unwillingness to comply with study requirements
•Patients who were previously taking statins for any reason
•Treatment approach for oral squamous cell carcinoma varies due to its unique challenges
•Patients undergoing treatment with anti-HIV drugs
•Having a history of other cancers
•Smoker patients
•Patients who are consumers of a specific medication
•Patients with specific systemic diseases
•Patients with a history of intolerance to statins
•Patients with acute liver failure
•Pregnant and lactating women
•consumption of another drug that interacts with atorvastatin
•consumption of Gemfibrozil medication
•consumption of Clarithromycin medication
•consumption of Cyclosporine medication
•consumption of Itraconazole medication
•consumption of Colchicine medication

发起方

Karaj University of Medical Sciences