IRCT20210113050023N1RecruitingPhase 3
The effect of Atorvastatin administration on the outcome of patients with traumatic brain injury
Trial Snapshot
- Phase
- Phase 3
- Status
- Recruiting
- Enrollment
- 60
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 years to 75 years (—)
- Sex
- All
Inclusion Criteria
- •Patients with moderate (GCS = 9.13) and severe (GCS = 8.5) brain trauma injuries based on GCS score
- •Patients with size of brain contusions less than 30 CC according to the initial CT-scan of the brain
- •No history of statins
- •Patients who arrived at the hospital less than 10 hours after the injury
- •their legal representative (guardian or trustee) will be present to receive the consent
Exclusion Criteria
- •Patients with GCS scores of 4 and 3
- •Patients with Grade IV on primary brain scan or CT scan
- •Patients with severe damage to other internal organs or spinal cord injury
- •History of kidney or liver disease
- •Creatine>2.5 mg/dl
- •History of brain tumor, stroke
- •History of infection
- •Previous craniotomy
- •Pregnant and lactating women
- •Patients with systolic blood pressure less than 90 mm Hg
- •History of taking low-molecular-weight anticoagulants such as aspirin, wafarin, or heparin (7 days before hospitalization)
Investigators
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