Effect of 1.5% Potassium Oxalate on the Control of Tooth Sensitivity and Color Change After Home Bleaching

Not Applicable

Completed

• Conditions: Dentin Sensitivity
• Interventions: Other: Carbamide Peroxide (PC) 22%) + placebo gel; Other: Carbamide Peroxide (PC) 22%) + Potassium Oxalate gel 1.5%

• Registration Number: NCT05028335
• Lead Sponsor: Universidade Federal do Para

Brief Summary

This double-blind randomized clinical trial evaluated the effect of 1.5% potassium oxalate on pain sensitivity control and color change after home tooth whitening. It also evaluated the influence of potassium oxalate on health-related quality of life (HRQOL) and on the degree of patient satisfaction after bleaching treatment.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-12-07
• Primary Completion: 2021-04-15
• Study Completion: 2021-06-05
• Study First Submitted: 2021-08-24
• Study First Submitted QC: 2021-08-24
• Study First Posted: 2021-08-31
• Status Verified: 2024-12
• Last Update Submitted: 2024-12-05
• Last Update Posted: 2024-12-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• individuals aged 18 to 29 years of both sexes with chroma greater than A2 in the upper incisors and canines, in the Vita Classical color scale;
• absence of active caries lesions
• patients who had never undergone bleaching therapy;
• good oral hygiene and no hypersensitivity to tactile and evaporative stimuli through the Visual Analog Pain Scale;

Exclusion Criteria

• patients undergoing fixed orthodontic treatment;
• patients with darkened non-vital teeth and/or with extensive restorations in molars;
• presence of cracks or fractures;
• patients allergic to the product, with the presence of gastroesophageal disorders and with dentinal exposure in anterior and/or posterior teeth.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
Group G1	Carbamide Peroxide (PC) 22%) + placebo gel	Home bleaching treatment (Carbamide Peroxide (PC) 22%) + placebo gel
Group G2	Carbamide Peroxide (PC) 22%) + Potassium Oxalate gel 1.5%	Home bleaching treatment (Carbamide Peroxide (PC) 22%) + 1.5% Potassium Oxalate gel

Primary Outcome Measures

Name	Time	Method
dental color assessment	21 days and 1 month after the bleaching treatment	Color evaluation was performed using the EasyshadeAdvanced spectrophotometer (Vita-Zahnfabrik, GE, Germany), using the CIE L\*a\*b\* system.
dentin sensitivity	21 days after the start of the whitening treatment	evaluation of dentinal sensitivity during treatment through a daily questionnaire, using a visual analogue scale with values from 0 to 10, with higher values indicating a worse level of pain.

Trial Locations

Locations (1)

Federal University of Pará; 🇧🇷 Belém, Pará, Brazil