Relationship Between Insulin Levels and Postprandial Hypotension in the Standard Mixed Meal Test in Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 111
- 试验地点
- 1
- 主要终点
- Blood glucose
研究概览
简要总结
The goal of this observational study is to learn about the relationship between postprandial hypotension and insulin levels in adults. The main question it aims to answer is:
Is the incidence of postprandial hypotension high in patients who undergo mixed meal test?
Is insulin level higher in individuals with postprandial hypotension compared to those without during a mixed meal test?
Patients with postprandial symptoms were scheduled for a mixed meal test, during which plasma glucose, insulin, C-peptide, blood pressure, and heart rate were measured at specific time points.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adults with postprandial symptoms
排除标准
- •Individuals with prediabetes or diabetes,
- •Those aged 65 and above,
- •Patients using antihypertensive medications or with known hypertension,
- •Those with active infections,
- •Congestive heart failure,
- •Peripheral artery disease,
- •Advanced-stage dementia,
- •Individuals who could not provide a history or were unable to cooperate,
- •Patients using medications that could induce hypoglycemia (oral antidiabetics, insulin, beta-blockers, hydroxychloroquine, bromocriptine, etc.)
- •Those with conditions that could cause hypoglycemia (uncontrolled hypothyroidism, adrenal insufficiency, growth hormone deficiency, etc.)
结局指标
主要结局
Blood glucose
时间窗: During mixed meal test (baseline, 30., 60., 90., 120., 180., 240., 300. min)
mg/dL
Systolic blood pressure
时间窗: During mixed meal test (baseline, 30., 60., 90., 120., 180., 240., 300. min)
mmHg
Blood insulin
时间窗: During mixed meal test (baseline, 30., 60., 90., 120., 180., 240., 300. min)
uIU/mL
次要结局
- Blood C-peptide(During mixed meal test (baseline, 30., 60., 90., 120., 180., 240., 300. min))
- Diastolic blood pressure(During mixed meal test (baseline, 30., 60., 90., 120., 180., 240., 300. min))
- Heart rate(During mixed meal test (baseline, 30., 60., 90., 120., 180., 240., 300. min))
研究者
Rahime Evra KARAKAYA
Principal Investigator
Ankara Yildirim Beyazıt University