A comparative study of radiofrequency ablation(RFA) with wound suturing versus trichloroacetic acid (TCA) 50% in the treatment of xanthelasma palpebrum.

A total of 46 patients presenting to the Department of Dermatology, Eras Lucknow Medical College and Hospital, Lucknow with clinical diagnosis of xanthelasma palpebrum will be approached for participation in the study. Patients meeting the inclusion and exclusion criteria and giving written consent for participating in the study shall be recruited. History and clinical examination with photographic documentation will be done before starting treatment and then at each visit. Patients will be randomly divided into two groups – A and B each containing 23 individuals. In group A – Patients will be advised to apply Trichloroacetic acid (50%) once in 2 weeks over the lesion for 6 weeks. In group B – Patients will be advised for radiofrequency ablation of the lesion followed by wound suturing. sutures will be removed after 1 week. Results will be noted at each follow up at 2, 4 and 6 weeks and at each follow-up visit clinical response will be determined based on reduction in size as Mild improvement(<25% clearance),Moderate improvement(25-50% clearance),Good improvement(50-75% clearance) and Excellent improvement(>75% clearance). Final outcome will be noted at the end of 6th week. Side effects will be noted at each visit.