Early Detection of Lung Cancer in the Medically Underserved Population
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 45
- 试验地点
- 2
- 主要终点
- Candidate biomarkers of risk or of early diagnosis
研究概览
简要总结
This research trial studies the long term follow-up for early detection of lung cancer in current or former smokers. Following up on smokers by collecting and analyzing specimens in the laboratory, performing chest computed tomography (CT) scans, as well as reviewing medical records may help doctors detect lung cancer at an earlier stage.
详细描述
PRIMARY OBJECTIVES:
I. To provide screening for lung cancer in an underserved and high risk population for lung cancer.
II. To collect clinical and demographic information and research bio specimens prospectively on high risk individuals.
III. To analyze the association between suspected lung cancer risk factors and outcomes such as pre-malignant lesions and diagnosis of lung cancer.
IV. To identify and validate biomarkers that are associated with lung cancer risk factors and premalignant lesions.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 55 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Current smoker or former smoker, if former smoker participants must have quit smoking within the past 15 years
- •>= 30 pack year of smoking history
- •Participant is uninsured
排除标准
- •History of diagnosis/treatment of lung cancer in the past 2 years
- •History of head/neck or esophageal cancer in the last 1 year
- •Inability to provide informed consent
结局指标
主要结局
Candidate biomarkers of risk or of early diagnosis
时间窗: Up to 5 years.
Will validate the performance of the candidate biomarkers of risk or of early diagnosis.
次要结局
未报告次要终点
研究者
Eric Grogan
Associate Professor of Thoracic Surgery
Vanderbilt-Ingram Cancer Center