Peri-articular multimodal cocktail drug injection after ACLR
Phase 2
Completed
- Conditions
- multimodal cocktail drugpost operative pain after Anterior Cruciate Ligament Reconstruction surgery with Hamstring graft.ACL Reconstructionpain controlperi-articular injection
- Registration Number
- TCTR20210216002
- Lead Sponsor
- /A
- Brief Summary
Peri-articular with peri-hamstring MCD injection can effectively reduce short-term postoperative pain and morphine consumption following arthroscopic ACL reconstruction with a hamstring graft.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
1. Patients diagnosed ACL injury that have to be performed ACLR (elective case)
2. Age 18 to 50 years
3. Normal Conciousness
4. Volunteer
Exclusion Criteria
1. ASA classification more than 3
2. Have history drug allergy (Bupivacaine, NSAIDs, Opioid)
3. Have history of UGIB
4. Chronic Kidney Disease stage 3 or GFR < 60 ml/min/1.73 m2
5. Underlying disease Ishemic Heart Disease, Cardio Vascular Disease, Platelet disorder. Coagulopathy
6. Usage of anti-coagulant drug
7. Have contraindication for Spinal Anesthesia or neurologic disorder
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method pain at 0,6,12,24,48 hours after ACLR surgery Visual Analogue Pain score
- Secondary Outcome Measures
Name Time Method IV Opioid drug use within 3 days after ACLR surgery amount of IV opioid drug use,functional score within 6 weeks after surgery IKDC score and Lysholm score,time to ambulation within 3 days after ACLR surgery time (hours),1st time IV Opioid use within 3 days after ACLR surgery time (hours),pain at 2 and 6 weeks after ACLR surgery Visual analogue pain score,range of motion of knee at 6 weeks after ACLR surgery degree,length of stay along admission admission days,Nausea/Vomiting within 3 days after ACLR surgery Nausea/Vomiting