Recovery profile of intraoperative Ketamine-Dexmedetomidine infusion versus Fentanyl- Dexmedetomidine infusion in patients undergoing General anaesthesia - A Randomised control study
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- To compare the recovery profile between the two groups.ketamine(0.5mg/kg/hr)and dexmedetomidine(0.5mcg/kg/hr) & fentanyl( 0.5mcg/kr/hr) and dexmedetomidine(0.5mcg/kg/hr) in the patients aged between 18 to 60 years undergoing general anesthesia
研究概览
简要总结
The thesis investigates the recovery outcomes associated with two different intraoperative analgesia regimens during general anesthesia: a Ketamine-Dexmedetomidine infusion versus a Fentanyl-Dexmedetomidine infusion. In this randomized controlled study, patients undergoing general anesthesia were divided into two groups, each receiving one of the two infusion combinations. The primary focus was to compare the recovery profiles of the two regimens, including parameters such as time to wakefulness, postoperative pain levels, and any side effects or complications. The study aims to determine which combination provides a better recovery experience for patients in terms of both efficacy and safety.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA 1 and 2 patients of either sex from 18-60 years of age undergoing major abdominal or head and neck surgeries.
排除标准
- •Patient refusal American Society of Anesthesiology Class 3 and more Known drug allergy Heart block Arrhythmias Respiratory disorder Renal & Hepatic dysfunction.
结局指标
主要结局
To compare the recovery profile between the two groups.ketamine(0.5mg/kg/hr)and dexmedetomidine(0.5mcg/kg/hr) & fentanyl( 0.5mcg/kr/hr) and dexmedetomidine(0.5mcg/kg/hr) in the patients aged between 18 to 60 years undergoing general anesthesia
时间窗: 0mins,5mins,10mins,15mins,20mins,25mins,30mins,45mins,60mins,75mins,90mins,105mins,120mins | after extubation 5mins,10mins,15mins
次要结局
- to compare the hemodynamic parameters between the two groups.ketamine(0.5mg/kg/hr)and dexmedetomidine(0.5mcg/kg/hr) & fentanyl( 0.5mcg/kr/hr) and dexmedetomidine(0.5mcg/kg/hr) in the patients aged between 18 to 60 years undergoing general anesthesia(0mins,5mins,10mins,15mins,20mins,25mins,30mins,45mins,60mins,75mins,90mins,105mins,120mins)
研究者
Uthayasankar
Sri Venkateshwaraa Medical College Hospital and Research Centre, Puducherry