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Clinical Trials/CTRI/2025/08/093390
CTRI/2025/08/093390Not yet recruitingPhase 3

Comparison of Dexmedetomidine and ketamine versus fentanyl and propofol for short surgical procedures under general anaesthesia

Vinayaka Missions Kirupananda Variyar Medical College and Hospitals Chinnaseeragapadi Salem1 site in 1 country60 target enrollmentStarted: September 8, 2025Last updated:
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Trial Snapshot

Phase
Phase 3
Status
Not yet recruiting
Sponsor
Enrollment
60
Locations
1
Primary Endpoint
To compare the efficacy of dexmedetomidine and ketamine versus fentanyl and propofol for intraoperative analgesia and anaesthesia and to assess hemodynamic stability
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

This Study Compares Dexmedetomidine and ketamine versus fentanyl and propofol for short surgical procedures under general anaesthesia

Study Design

Study Type
Interventional
Allocation
Na
Masking
Participant and Investigator Blinded

Eligibility Criteria

Ages
18.00 Year(s) to 65.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • •Age between
  • •60 years (Both Males and Females) ASA Grade 1 and 2 Undergoing Short Surgical Procedures (less than 60 mins).

Exclusion Criteria

  • •Patient refusal ASA grade 3 and 4 Posted for Emergency Surgeries Allergy to Propofol and dexmedetomidine CVS Disorders Liver or Renal Dysfunction.

Outcomes

Primary Outcomes

To compare the efficacy of dexmedetomidine and ketamine versus fentanyl and propofol for intraoperative analgesia and anaesthesia and to assess hemodynamic stability

Time Frame: From 15 mins to 1 hour Intraoperatively

Secondary Outcomes

  • To compare postoperative recovery profiles including emergence time,sedation,pain score & incidence of postoperative nausea & vomiting between dexmedetomidine & ketamine & fentanyl & propofol groups(From 15 mins to 6 hour postoperatively in PAICU)

Investigators

Sponsor
Vinayaka Missions Kirupananda Variyar Medical College and Hospitals Chinnaseeragapadi Salem
Sponsor Class
Private medical college
Responsible Party
Principal Investigator
Principal Investigator

Dr R Brindha

Vinayaka Missions Kirupananda Variyar Medical College and Hospitals Chinnaseeragapadi Salem

Study Sites (1)

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