The Impact of Metabolic Syndrome on Patients Undergoing Elective Laparotomy
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Metabolic Syndrome
- Sponsor
- University of Ioannina
- Enrollment
- 105
- Primary Endpoint
- Acute Kidney Injury (AKI) as defined by Kidney Disease Improving Global Outcomes (KDIGO) guidelines
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
Worldwide, the rising incidence of obesity has led to the identification of an obesity related syndrome, called metabolic. This syndrome is characterized by central obesity, hypertension, insulin resistance and altered lipid levels.
Taking into consideration the rising incidence of obesity, anesthetists will more frequently encounter patients with metabolic syndrome, in their everyday practice. Moreover, the comorbidities that are related to the metabolic syndrome, increase the risk for perioperative complications. Therefore, strategies that will evaluate and modify the risk will be of great importance in the management of these patients, in order to maximize peri-anaesthetic and surgical safety.
The aim of the study is to assess the incidence of metabolic syndrome and the impact of its presence on the outcome of patients undergoing elective laparotomy.
Investigators
Petros Tzimas
Assistant Professor of Anaesthesiology
University of Ioannina
Eligibility Criteria
Inclusion Criteria
- •Adult patients are undergoing elective laparotomy of estimated duration of more than one hour. All operations will be performed under general anesthesia.
Exclusion Criteria
- •Endstage neoplasia
- •Procedures performed within 1 hour of admission
- •Emergency cases
Outcomes
Primary Outcomes
Acute Kidney Injury (AKI) as defined by Kidney Disease Improving Global Outcomes (KDIGO) guidelines
Time Frame: 2 Weeks
Surgical site infection (superficial or deep) as defined by European Perioperative Clinical Outcome (EPCO) definitions guidelines.
Time Frame: 2 Weeks
Postoperative pulmonary complications as defined by European Perioperative Clinical Outcome (EPCO) definitions guidelines.
Time Frame: 2 Weeks
Perioperative and postoperative adverse cardiac and cerebrovascular events as defined by European Perioperative Clinical Outcome (EPCO) definitions guidelines.
Time Frame: 2 Weeks