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Clinical Trials/NCT04868331
NCT04868331
Completed
Not Applicable

Evaluation of Cardiovascular Responses in Adolescent Idiopathic Scoliosis (AIS) Girls Performing E-Fit Exercise Intervention: a Pilot Study

Tung Wah College1 site in 1 country20 target enrollmentMay 18, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Adolescent Idiopathic Scoliosis
Sponsor
Tung Wah College
Enrollment
20
Locations
1
Primary Endpoint
Oximetry
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The aims of this pilot study are to determine the metabolic demand and exercise intensity level of E-Fit exercise intervention by evaluating the cardiovascular responses in AIS girls and whether the cardiovascular responses for AIS girls performing E-Fit will behave in the same way as compared to healthy controls. We hypothesise that 1) the metabolic demand and exercise intensity of E-Fit exercise intervention is equivalent to moderate-to-vigorous level; and 2) AIS girls have different cardiovascular responses as compared to healthy controls

Detailed Description

AIS girls and age- and gender-matched healthy controls will perform the E-Fit exercise intervention for two trials and gas exchange parameters including oxygen consumption (VO2) and carbon dioxide production (VCO2) will be taken continuously during the exercise. Comparison of VO2 and VCO2 between AIS and healthy controls when performing E-Fit exercise will be made.

Registry
clinicaltrials.gov
Start Date
May 18, 2021
End Date
March 12, 2022
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Sponsor
Tung Wah College
Responsible Party
Principal Investigator
Principal Investigator

Rufina Lau

Senior Lecturer

Tung Wah College

Eligibility Criteria

Inclusion Criteria

  • Cobb angle greater or equal to 15 degree
  • Cleared for physical activity by doctor

Exclusion Criteria

  • Cobb angle greater or equal to 40 degree, or
  • Scoliosis with any known etiology, scoliosis with skeletal dysplasia, know endocrine and connective tissue abnormalities, or
  • Known heart condition or other diseases that could affect the safety of exercise, or
  • Eating disorders or GI malabsorption disorders, or
  • Currently taking medication that affects bone or muscle metabolism

Outcomes

Primary Outcomes

Oximetry

Time Frame: Day 1

Peripheral capillary oxygen saturation (%) will be measured using a fingertip oximeter.

Respiratory gas measurement

Time Frame: Day 1

Breath-by-breath measurement of cardiorespiratory and gas exchange parameters to analyse oxygen consumption (VO2 in ml/min) and carbon dioxide production (VCO2 in ml/min).

Blood Pressure

Time Frame: Day 1

Blood pressure (mmHg) will be measured using an electronic sphygmomanometer.

Heart rate

Time Frame: Day 1

Heart rate (bpm) will be measured using a fingertip oximeter.

Secondary Outcomes

  • Modified Baecke Questionnaire(Day 1)
  • Body Composition(Day 1)
  • Sitting height(Day 1)
  • Arm Span(Day 1)
  • Maturity assessment(Day 1)
  • Physical Activity Rating Questionnaire for Children and Youth (PARCY)(Day 1)
  • Body height(Day 1)

Study Sites (1)

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