Dexmedetomidine vs Fentanyl in Controlling Labor Pain
- Registration Number
- NCT06392321
- Lead Sponsor
- Al-Azhar University
- Brief Summary
As most woman experience agonizing pain throughout vaginal labor. Adjuvants were added to intrathecal bupivacaine aiming to improve the quality of analgesia. This study aimed to assess the efficacy and outcome of intrathecal dexmedetomidine and fentanyl in controlling pain during delivery.
- Detailed Description
Throughout vaginal deliveries, many women suffered from pain. providing suitable analgesia is crucial (Lupu et al., 2023). Spinal anesthesia can provide pain management (Parikh et al., 2018).
Various types of analgesics can be combined to get the needed duration of perioperative analgesia. Dexmedetomidine has been used with effective pain management outcomes (Shrestha et al., 2023). Fentanyl can help pain relief in short duration procedures (Show et al., 2022).
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 90
- women planned for spontaneous vaginal delivery.
- cardiac, liver or kidney disease, allergy to local anesthetics or the studied drugs, any contraindication of regional anesthesia and intrauterine growth retardation or fetal compromise.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Dexmedetomidine Dexmedetomidine Bupivacaine 3,75 mg + 2.5 ml saline added to dexmedetomedine 5 microgram + 2.3 ml saline Fentanyl Fentanyl Bupivacaine 3,75 mg + 2.5 ml saline added to fentanyl 20 microgram + 2.3 ml saline
- Primary Outcome Measures
Name Time Method efficacy of intrathecal dexmedetomidine 120 minutes VAS
- Secondary Outcome Measures
Name Time Method patient satisfaction 2 hours satisfaction score
mother's outocme 1 and 5 minutes APGAR
Trial Locations
- Locations (1)
Al Azhar University
🇪🇬Cairo, Naser City, Egypt