The Effect of Dexmedetomidine in the Management of Pain After Uterine Artery Embolization

Not Applicable

Completed

• Conditions: Pain Control
• Interventions: Drug: Normal saline 0.9%; Drug: Dexmedetomidine

• Registration Number: NCT01578174
• Lead Sponsor: Severance Hospital

Brief Summary

The investigators examined the effect of dexmedetomidine in the management of pain after uterine artery embolization.

Detailed Description

Leiomyoma are the most common female reproductive tract tumors. Uterine artery embolization(UAE) is a minimally invasive treatment alternative to hysterectomy and myomectomy. However, post-procedural pain control after UAE remains a major problem. Therefore, the aim of study is to evaluate the efficacy of dexmedetomidine in pain control after UAE.

Study Timeline

• Study Start: 2012-04
• Study First Submitted: 2012-04-13
• Study First Submitted QC: 2012-04-13
• Study First Posted: 2012-04-16
• Primary Completion: 2012-09
• Study Completion: 2012-09
• Status Verified: 2018-01
• Last Update Submitted: 2018-01-16
• Last Update Posted: 2018-01-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 66

Inclusion Criteria

• age ≥ 20,
• ASA class I and II

Exclusion Criteria

• bradycardia (< 45 bpm)
• heart block
• liver failure
• renal failure
• uncontrolled hypertension
• body mass index ≥ 30 kg/m2

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control	Normal saline 0.9%	-
Dexmedetomidine	Dexmedetomidine	-

Primary Outcome Measures

Name	Time	Method
Fentanyl consumption by patient-controlled analgesia	24 hours

Secondary Outcome Measures

Name	Time	Method
Side effects	24 hours

Trial Locations

Locations (1)

Department of Anesthesiology and Pain Medicine and Anesthesia and Pain Research Institute, Yonsei University College of Medicine; 🇰🇷 Seoul, Korea, Republic of