NL-OMON23633已完成不适用
The effect of dietary lactose in lactase non-persistent individuals on gut microbiota
Wageningen Food & Biobased Research0 个研究点目标入组 25 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 25
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •Apparently healthy men and women (based on questionnaire)
- •Asian ethnicity
- •Age between 18 and 50 years
- •Body mass index (BMI) between 18.5 and 30 kg/m2
- •LNP genotype (based on buccal swab testing)
- •Avoiding dietary lactose in habitual diet (self-reported via questionnaire)
- •Regular stool frequency (on average at least once every two days)
排除标准
- •Any metabolic, gastrointestinal, inflammatory or chronic disease (such as diabetes, anaemia, hepatitis, cardiovascular disease), judged by the medical doctor
- •History of gastro-intestinal surgery or having (serious) gastrointestinal discomfort
- •Use of pre- and/or probiotics
- •Use of medication that may influence the study results, such as laxatives and lactase preparations (e.g. Kerutab). Use of medication will be judged by the medical supervisor.
- •Having used antibiotics in the 6 months prior to the start of the study
- •Reported slimming or medically prescribed diet
- •Current smokers
- •Alcohol intake =2 (women) or =4 (men) glasses of alcoholic beverages per day
- •Pregnant or lactating (or having the wish to become pregnant during the study period, self-reported)
- •Abuse of illicit drugs
- •Having food allergies (food intolerances are acceptable)
- •Insufficient proficiency in English to understand information brochure and questionnaires
- •Participation in another clinical trial at the same time
- •Being an employee of the department Consumer Science & Health group of Wageningen Food & Biobased Research, Human Nutrition Department of Wageningen University, or FrieslandCampina.
研究者
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