Comparative study of 0.5% Levo-bupivacaine versus 0.5% Ropivacaine in combined sciatic and femoral nerve block in below knee orthopedic surgery under ultrasound guidance.
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 46
- 试验地点
- 1
- 主要终点
- To evaluate the efficacy of 0.5% Levo-bupivacaine versus 0.5% Ropivacaine in combined sciatic and femoral nerve block under ultrasound guidance in patients undergoing below knee orthopaedic surgery
研究概览
简要总结
Regional anaesthesia are increasingly the preferred and best option for wide range of lower limb surgeries.It is said to provide surgical anaesthesia with better cardio- respiratory stability and to cause least interferance with the vital physiological function of the body.
Levo-bupivacaine has strongly emerged as a safer alternative for regional anaesthesia and is less cardiotoxic. Ropivacaine is documented to have comparable levels and duration of analgesia, lesser cardiotoxicity for the same duration of analgesia in comparison to Bupivacaine.
The purpose of the present study is to evaluate the efficacy of 0.5% Levo-bupivacaine and 0.5% Ropivacaine in combined sciatic and femoral nerve block for below knee orthopaedic surgery, by studying the onset and duration of sensory and motor blockade and the hemodynamic changes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •ASA grade 1 and 2, no known neurological deficit, surgery.
- •orthopaedic surgery below knee.
排除标准
- •ASA grade 3 and 4, patient with neurological disorders, history of allergy to study drug.
结局指标
主要结局
To evaluate the efficacy of 0.5% Levo-bupivacaine versus 0.5% Ropivacaine in combined sciatic and femoral nerve block under ultrasound guidance in patients undergoing below knee orthopaedic surgery
时间窗: After induction | End of surgery | 12 hour postoperative
次要结局
- To study hemodynamic changes of 0.5% Levo-bupivacaine and 0.5% Ropivacaine(After induction)
研究者
Dr Prity Rani Tirkey
Rajendra institute of medical science, Ranchi
