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临床试验/CTRI/2024/07/070390
CTRI/2024/07/070390尚未招募4 期

Comparative study of 0.5% Levo-bupivacaine versus 0.5% Ropivacaine in combined sciatic and femoral nerve block in below knee orthopedic surgery under ultrasound guidance.

Rajendra institute of medical science1 个研究点 分布在 1 个国家目标入组 46 人开始时间: 2024年7月20日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
46
试验地点
1
主要终点
To evaluate the efficacy of 0.5% Levo-bupivacaine versus 0.5% Ropivacaine in combined sciatic and femoral nerve block under ultrasound guidance in patients undergoing below knee orthopaedic surgery

研究概览

简要总结

Regional anaesthesia are increasingly the preferred and best option for wide range of lower limb surgeries.It is said to provide surgical anaesthesia with better cardio- respiratory stability and to cause least interferance with the vital physiological function of the body.

Levo-bupivacaine has strongly emerged as a safer alternative for regional anaesthesia and is less cardiotoxic. Ropivacaine is documented to have comparable levels and duration of analgesia, lesser cardiotoxicity for the same duration of analgesia in comparison to Bupivacaine.

The purpose of the present study is to evaluate the efficacy of 0.5% Levo-bupivacaine and 0.5% Ropivacaine in combined sciatic and femoral nerve block for below knee orthopaedic surgery, by studying the onset and duration of sensory and motor blockade and the hemodynamic changes.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • ASA grade 1 and 2, no known neurological deficit, surgery.
  • orthopaedic surgery below knee.

排除标准

  • ASA grade 3 and 4, patient with neurological disorders, history of allergy to study drug.

结局指标

主要结局

To evaluate the efficacy of 0.5% Levo-bupivacaine versus 0.5% Ropivacaine in combined sciatic and femoral nerve block under ultrasound guidance in patients undergoing below knee orthopaedic surgery

时间窗: After induction | End of surgery | 12 hour postoperative

次要结局

  • To study hemodynamic changes of 0.5% Levo-bupivacaine and 0.5% Ropivacaine(After induction)

研究者

发起方
Rajendra institute of medical science
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Prity Rani Tirkey

Rajendra institute of medical science, Ranchi

研究点 (1)

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