Comparative study of 0.5% Levo-bupivacaine versus 0.5% Ropivacaine in combined sciatic and femoral nerve block in below knee orthopedic surgery under ultrasound guidance.
Trial Snapshot
- Phase
- Phase 4
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 46
- Locations
- 1
- Primary Endpoint
- To evaluate the efficacy of 0.5% Levo-bupivacaine versus 0.5% Ropivacaine in combined sciatic and femoral nerve block under ultrasound guidance in patients undergoing below knee orthopaedic surgery
Study Overview
Brief Summary
Regional anaesthesia are increasingly the preferred and best option for wide range of lower limb surgeries.It is said to provide surgical anaesthesia with better cardio- respiratory stability and to cause least interferance with the vital physiological function of the body.
Levo-bupivacaine has strongly emerged as a safer alternative for regional anaesthesia and is less cardiotoxic. Ropivacaine is documented to have comparable levels and duration of analgesia, lesser cardiotoxicity for the same duration of analgesia in comparison to Bupivacaine.
The purpose of the present study is to evaluate the efficacy of 0.5% Levo-bupivacaine and 0.5% Ropivacaine in combined sciatic and femoral nerve block for below knee orthopaedic surgery, by studying the onset and duration of sensory and motor blockade and the hemodynamic changes.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- Participant and Investigator Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •ASA grade 1 and 2, no known neurological deficit, surgery.
- •orthopaedic surgery below knee.
Exclusion Criteria
- •ASA grade 3 and 4, patient with neurological disorders, history of allergy to study drug.
Outcomes
Primary Outcomes
To evaluate the efficacy of 0.5% Levo-bupivacaine versus 0.5% Ropivacaine in combined sciatic and femoral nerve block under ultrasound guidance in patients undergoing below knee orthopaedic surgery
Time Frame: After induction | End of surgery | 12 hour postoperative
Secondary Outcomes
- To study hemodynamic changes of 0.5% Levo-bupivacaine and 0.5% Ropivacaine(After induction)
Investigators
Dr Prity Rani Tirkey
Rajendra institute of medical science, Ranchi