The Effect of Peripartum Magnesium Sulfate Use on the Occurrence of Postpartum Depression

Recruiting

• Conditions: Postpartum Depression
• Interventions: Drug: Magnesium sulfate

• Registration Number: NCT05751746
• Lead Sponsor: Seoul National University Bundang Hospital

Brief Summary

This is an observational study that will be conducted on pregnant women under vaginal delivery or cesarean section. The magnesium sulfate will be given to appropriate participants with a protocol that obstetrician are already using in our hospital. After delivery, participants are asked to answer sequential questionnaires to assess postpartum depression.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-30
• Study First Submitted: 2023-01-30
• Status Verified: 2023-02
• Study First Submitted QC: 2023-02-26
• Last Update Submitted: 2023-02-26
• Study First Posted: 2023-03-02
• Last Update Posted: 2023-03-02
• Primary Completion: 2023-12-31
• Study Completion: 2024-02-28

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 108

Inclusion Criteria

• Pregnant women who will do delivery.
• Gestational week >= 30 week
• Singleton

Exclusion Criteria

• History of depression

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Magnesium group	Magnesium sulfate	Intervention group with participants who get magnesium sulfate administration.

Primary Outcome Measures

Name	Time	Method
postpartum depression	6 week after discharge	depression diagnosis using K-EPDS(Korean version of Edinburgh Postnatal Depression Scale) on a scale of 7 to 30 points.
postpartum depression severity	6 week after discharge	depression severity using K-EPDS; mild (7\~13 points), moderate (14\~19 points), severe (20\~30 points)

Secondary Outcome Measures

Name	Time	Method
postpartum depression	2week after discharge	depression diagnosis using K-EPDS(Korean version of Edinburgh Postnatal Depression Scale) on a scale of 7 to 30 points.
postpartum depression severity	2 week after discharge	depression severity using K-EPDS; mild (7\~13 points), moderate (14\~19 points), severe (20\~30 points)

Trial Locations

Locations (1)

Seoul National University Bundang Hospital; 🇰🇷 Seongnam-si, Gyeonguido, Korea, Republic of