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Clinical Trials/NCT04416230
NCT04416230
Completed
Not Applicable

The Effects of Massage on Pain After Pediatric Cardiothoracic Surgery

Ohio State University0 sites65 target enrollmentMay 1, 2012

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Congenital Heart Disease
Sponsor
Ohio State University
Enrollment
65
Primary Endpoint
Post-operative pain score
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

The primary aims of the proposed study are to pilot test the effectiveness of daily massage on pain and clinical outcomes in infants who have undergone cardiothoracic surgery. The secondary aim is to explore relationships among massage, pain scores, and other variables potentially affecting pain scores, including parental anxiety, severity of cardiac defect, and severity of pain.

Specific Aim 1: To compare effects of massage on infant pain and clinical outcomes between two groups over time: infants receiving post-operative massage seven days post-operatively and infants receiving a comparable time of restricted non-essential caregiving seven days post-operatively.

Specific Aim 2: To compare pain scores and physiologic responses before and after intervention in two groups: infants receiving post-operative massage and infants receiving a comparable time of restricted non-essential caregiving.

Specific Aim 3: To examine potential moderators of pain response in the massage intervention group before and after receiving massage.

Detailed Description

We used a two-group randomized clinical trial design with a sample of 60 infants with complex congenital heart disease (CCHD) between 1 day and 12 months of age following their first cardiothoracic surgery. Both groups received standard post-operative care. In addition, Group 1 received a daily 30-minute restricted non-essential direct caregiving time (Quiet Time), and Group 2 received a daily 30-minute massage. Interventions continued for seven consecutive days. Pain was measured 6 times daily using the Face, Legs, Activity, Cry, Consolability Pain Assessment Tool (FLACC). Average daily doses of analgesics were recorded. Heart rates (HR), respiratory rates (RR), and oxygen saturations (SpO2) were recorded continuously. Daily averages and pre- and post- intervention FLACC scores and physiologic responses were analyzed using descriptive statistics, generalized linear mixed models (GLMM) for repeated measures, latent growth models, and/or regression discontinuity analysis. Fentanyl-equivalent narcotic values were used as a time-varying covariate.

Registry
clinicaltrials.gov
Start Date
May 1, 2012
End Date
May 30, 2014
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Tondi Harrison

Principal Investigator

Ohio State University

Eligibility Criteria

Inclusion Criteria

  • Infants born with complex congenital heart disease requiring surgical intervention
  • less than 12 months old
  • undergoing first surgical procedure

Exclusion Criteria

  • on paralytics post-operatively
  • cardiorespiratory instability
  • on-going cardiac pacing

Outcomes

Primary Outcomes

Post-operative pain score

Time Frame: Daily average for 7 days

FLACC score: behavioral observation of face, legs, activity, cry, consolability

Heart rate

Time Frame: Daily average for 7 days

heart rate in beats per minute

Respiratory rate

Time Frame: Daily average for 7 days

respiratory rate in breaths per minute

Change in respiratory rate with intervention

Time Frame: Daily for 7 days

respiratory rate in beats per minute

Change in oxygen saturation with intervention

Time Frame: Daily for 7 days

oxygen saturation percentage

Change in post-operative pain score with intervention

Time Frame: Daily for 7 days

FLACC score: behavioral observation of face, legs, activity, cry, consolability

Oxygen saturation

Time Frame: Daily average for 7 days

oxygen saturation percentage

Change in heart rate with intervention

Time Frame: Daily for 7 days

heart rate in beats per minute

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