To compare the effects of magnesium sulphate and low dose of dexmedetomidine on pulse, BP of patients undergoing laparoscopic cholecystectomy under anaesthesia.

Not Applicable

Not yet recruiting

• Conditions: Persons encountering health services in other circumstances,

• Registration Number: CTRI/2018/09/015841
• Lead Sponsor: No

Brief Summary

Aim is to compare effect of magnesium sulphate and low dose of dexmedetomidine on haemodynamic parameters in patients undergoing laparoscopic cholecystectomy under general anaesthesia,under 1%isoflurane and thiopentone as laparoscopic procedures cause various haemodynamic changes therefore we compare both the drugs as to stabilize haemodynamic parameters and which drug is superior over the other.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2018-09-25
• Study Start: 2018-09-30

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Patients scheduled for elective laparoscopic cholecystectomy under general anaesthesia.
• Aged between 18-60yrs.
• Belonging to ASA1.

Exclusion Criteria

• History of cardiovascular diseases like hypertension, ischaemic heart disease,conduction defects etc.
• History of compromised renal/hepatic/neuronal functions.
• Pregnant/lactating women Endocrine diseases eg.
• Diabetes mellitus,hyper and hypothyroidism.
• Patient on any drug affecting cardiovascular parameters eg.CCB,beta blockers, magnesium sulphate etc.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare SBP in patients of two groups during pneumoperitoneum	To compare SBP in patients of two groups during pneumoperitoneum pre induction,just after induction at 1 and 3 min,post induction, during pneumoperitoneum at interval of 10 minutes,after desufflation and after extubation.

Secondary Outcome Measures

Name	Time	Method
To compare HR, DBP and MAP during pneumoperitoneum	Preinduction,after induction,and post intubation at 1,3 min, before pneumoperitoneum, during pneumoperitoneum at interval of 10 minutes,before desufflation,after desufflation,and after extubation.

Trial Locations

Locations (1)

Guru teg bahadur hospital; 🇮🇳 East, DELHI, India

Guru teg bahadur hospital

🇮🇳East, DELHI, India

Dr Mahendra kumar

Principal investigator

9968399709

mahendramohit@yahoo.com