Brain health in retired athletes

Not Applicable

• Conditions: eurodegenerative disease; Nervous System Diseases; Neurodegenerative disease

• Registration Number: ISRCTN11312093
• Lead Sponsor: The International Concussion and Head Injury Research Foundation (ICHIRF)

Brief Summary

2022 Results article in https://pubmed.ncbi.nlm.nih.gov/36111130/ (added 20/09/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-08-12
• Last Update Posted: 22 January 2024
• Study Completion: 2025-12-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 159

Inclusion Criteria

1. Completed the online screening assessment
2. Participated in elite sport
3. Can understand and participate in the testing procedures
4. Are able to provide informed consent for participation

Exclusion Criteria

1. For the questionnaire study if they are aged <18 years and ineligible for the phenotyping <50 years
2. Have a history of previous severe traumatic brain injury
3. Are on current psychotropic medication
4. They have a pre-existing medically-diagnosed neurological disorder (e.g. Alzheimer’s dementia, Parkinson’s disease, Multiple Sclerosis, Motor Neuron Disease)
5. The participant is currently enrolled in a disease modifying therapeutic (drug or interventional) trial
6. Presence of any of the following clinical conditions: Substance abuse within the past year; Unstable cardiac, pulmonary, renal, hepatic, endocrine, hematologic, or active malignancy or infectious disease; AIDS or AIDS-related complex; Unstable psychiatric illness defined as psychosis (hallucinations or delusions) or untreated major depression within 90 days of the screening visit

Study & Design

• Study Type: Observational
• Study Design: Not specified