A comparative study of Neutrophil to lymphocyte ratio, Platelet to lymphocyte ratio, and mean platelet volume to platelet count ratio as biomarkers in patients with sepsis assessed using qSOFA and APACHE2 criteria
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Predictive performance of baseline Neutrophil to lymphocyte ratio, Platelet to lymphocyte ratio, and Mean platelet volume to platelet count ratio for 28 day all cause mortality in patients with sepsis
研究概览
简要总结
thos prospective observational cross sectional study aims to evaluate and compare the diagnostic and prognostic utility of NLR and MPV/P as biomarkers in patients with sepsis and to correlate this markers with established clinical severity scores qSOFA and APACHE 2 at tertiary care hospital
primary outcome will be 28 day all cause mortality and secondary outcome will be need for vasopressors support , duration of ICU stay and correlation of biomarkers trends with qSOFA and APACHE 2 scores
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •any patient with age more than 18 yr and in sepsis.
排除标准
- •age less than 18 years corticosteroid therapy antibiotics use before admission hematological disorder malignant disease chemotherapy or radiotherapy 1 month before.
结局指标
主要结局
Predictive performance of baseline Neutrophil to lymphocyte ratio, Platelet to lymphocyte ratio, and Mean platelet volume to platelet count ratio for 28 day all cause mortality in patients with sepsis
时间窗: baseline biomarker measurements- within 24 hours of hospital admission | primary endpoint assessment- 28 days after enrolment
次要结局
- 28 day mortality OR ICU admission OR need for vasopressors / mechanical ventilation can also be predicted(28 days)
研究者
Dr Shubham deepak gonjari
Metrounited healthcare, shivamogga