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Clinical Trials/CTRI/2023/10/059333
CTRI/2023/10/059333Not yet recruitingUnknown

Evaluation of Neutrophil to Lymphocyte (NLR),Platelet to lymphocyte (PLR) and Lymphocyte to Monocyte (LMR) ratios in peripheral blood of patients having periodontitis with type 2 diabetes mellitus before and one month after scaling and root planing - NI

Dr. Nikita Vikasrao Palkar0 sites0 target enrollmentStarted: TBDLast updated:

Trial Snapshot

Phase
Unknown
Status
Not yet recruiting
Sponsor

Study Overview

Brief Summary

No summary available.

Study Design

Study Type
Interventional

Eligibility Criteria

Inclusion Criteria

  • 1.Subjects with clinically healthy periodontium, with no attachment loss and probing depth of less than or equal to 3 mm, <10%bleeding sites, subject with gingival index score of maximum up to <1, included which were considered to be relatively healthy and subject having HbA1c level between 4%–6% considered as control group.
  • 2.Group B:
  • 1.Patients with Periodontitis stage II and stage III as per the 2017 American Academy of Periodontology Classification.
  • 2.Patients with periodontitis stage II having clinical attachment loss of 3-4mm and maximum probing pocket depth =5 mm.
  • 3.Patients with periodontitis stage III having clinical attachment loss of =5 mm and maximum probing pocket depth = 6mm.35
  • 3.Group C:
  • 1.Patients with periodontitis (stage II and stage III as per the 2017 American Academy of Periodontology classification) with diagnosed case of type 2 diabetes mellitus (Good diabetes control, HbA1c level 7%)

Exclusion Criteria

  • 1.Patient refusal
  • 2.Patient who has received periodontal treatment in last 6months.
  • 3.Patient who is smoker or consuming any other form of tobacco.
  • 4.Pregnant, lactating or postmenopausal women.
  • 5.Hospitalized patients.
  • 6.Subjects consuming antibiotic or other drugs in the past 6 months that affect their periodontal status.
  • 7.History of any systemic disease which influences the values of NLR, PLR, and LMR ratio like any malignancy, cardiovascular diseases, rheumatic diseases, bipolar disorder, thyrotoxicosis, psoriasis other than type 2 diabetes mellitus for the test group (Group III)
  • 8.History of any systemic disease for the control group.
  • 9.If subject cannot maintain oral hygiene after non-surgical periodontal therapy (Gingival index score >1, plaque index >1).

Investigators

Sponsor
Dr. Nikita Vikasrao Palkar

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