NCT00186680
Completed
Phase 1
Selection of CD34+THY-1 Positive Cells From Peripheral Blood Cells Procured for Autologous Hematopoietic Support Following High Dose Treatment With BCNU, Cyclophosphamide & Cisplatin for Stage IV Breast Cancer & Limited Prior Treatment
ConditionsBreast Cancer
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Breast Cancer
- Sponsor
- Stanford University
- Enrollment
- 99
- Locations
- 1
- Primary Endpoint
- Feasibility and safety
- Status
- Completed
- Last Updated
- 16 years ago
Overview
Brief Summary
Evaluate the feasibility and safety of autologous transplantation of CD34+Thy-1+ hematopoietic stem cells afer high dose marrow ablative chemotherapy in patients with breast cancer.
Detailed Description
Selection of CD34+THY-1 Positive Cells From Peripheral Blood Cells Procured for Autologous Hematopoietic Support Following High Dose Treatment with BCNU, Cyclophosphamide \& Cisplatin for Stage IV Breast Cancer \& Limited Prior Treatment
Investigators
Eligibility Criteria
Inclusion Criteria
- •stage IV breast cancer
- •primary breast cancer does not express CD34+
- •adequate organ function
- •no evidence of active infection
Exclusion Criteria
- •chemotherapy within 4 weeks
- •CNS disease
Outcomes
Primary Outcomes
Feasibility and safety
Secondary Outcomes
- efficiency of mobilization
- tumor contamination
Study Sites (1)
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