Randomised controlled trial of surveillance and no surveillance for patients with Barrett's oesophagus

Not Applicable

Completed

• Conditions: Barrett's oesophagus; Digestive System

• Registration Number: ISRCTN54190466
• Lead Sponsor: Gloucestershire Royal NHS Foundation Trust (UK)

Brief Summary

2015 Protocol article in http://www.ncbi.nlm.nih.gov/pubmed/25767103 protocol

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2008-01-08
• Study Completion: 2022-06-30
• Last Update Posted: 5 August 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 3520

Inclusion Criteria

Patients over 18 with endoscopic and histologically proven barrett's oesophagus greater than 1 cm

Exclusion Criteria

1. Unable to give consent
2. Unable to tolerate upper gastrointestinal endoscopy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. All causes mortality<br>2. Death from adenocarcinoma<br>3. Development of treatable adenocarcinoma <br>Duration of follow-up: 10 years

Secondary Outcome Measures

Name	Time	Method
1. Quality of life: Reflux Questionnaire and EQ50 Quality of Life Questionnaire at yearly intervals by post<br>2. Cost effectiveness of endoscopy