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Clinical Trials/NL-OMON27107
NL-OMON27107CompletedNot Applicable

Influence of Mannose-Binding Lectin Polymorphisms on Infectious Complications in Trauma Patients.

Erasmus MC0 sites450 target enrollmentStarted: TBDLast updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Erasmus MC
Enrollment
450

Study Overview

Brief Summary

Bronkhorst MWGA, Boyé NDA, Lomax MAZ, Vossen RHAM, Bakker J, Patka P, Van Lieshout EMM. Single Nucleotide Polymorphisms in the Toll-Like Receptor Pathway increase Susceptibility to Infections in Severely Injured Trauma Patients. J Trauma Acute Care Surg 2013 Mar;74(3):862-870.

Bronkhorst MWGA, Lomax MAZ, Vossen RHAM, Bakker J, Patka P, Van Lieshout EMM. Risk of infection and sepsis in severely injured patients related to single nucleotide polymorphisms in the lectin pathway. Br J Surg. 2013 Dec;100(13):1818-26.

Study Design

Study Type
Observational

Eligibility Criteria

Inclusion Criteria

  • 1. Trauma patients with an ISS of 16 or higher:
  • 2. Age between 18 and 70 years;

Exclusion Criteria

  • 1. ISS<16;
  • 2. Age <18 or >70 years;

Investigators

Sponsor
Erasmus MC

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