Effects of high-intensity laser therapy as an adjunct to physiotherapy in knee osteoarthritis

Not Applicable

Conditions: Knee Osteoarthritis (KOA)
Musculoskeletal - Osteoarthritis
Physical Medicine / Rehabilitation - Other physical medicine / rehabilitation

Registration Number: ACTRN12624000699561

Lead Sponsor: Geran Galakan Penyelidik Muda (GGPM),under Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur.

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot yet recruiting

Sex: All

Target Recruitment: 40

Inclusion Criteria

i.Adults aged 18 years and above of both sexes.
ii.Individuals diagnosed with unilateral or bilateral KOA by an orthopaedic doctor.
iii.Those with a Kellgren-Lawrence classification of mild to moderate KOA based on a knee radiograph conducted within the last six months
iv.Individuals capable of engaging in the intervention and assessment program without restrictions. In cases where both knee joints are affected, the knee with more severe symptoms, based on the pain score, will be included. If symptoms are identical in both knees, the dominant knee will be assessed.

Exclusion Criteria

i.Presence of other pathological conditions like rheumatic disease, prior hip or knee joint replacement, congenital dysplasia, osteochondritis dissecans, intra-articular fractures, septic arthritis, ligament or meniscus injury, and any other condition impeding the healing process, including diabetes mellitus and peripheral vascular disease
ii.comorbidities hindering physical evaluation
iii.ongoing participation in another KOA-related interventional study
iv.individuals taking prescription glucosamine sulfate, which might potentially affect the study's outcomes.
v.Participants who had undergone intra-articular knee injections (e.g., corticosteroid, hyaluronic acid, or blood-derived products) for KOA management in the last six months

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Knee Injury and Osteoarthritis Outcome Score (KOOS): This validated questionnaire assesses the outcomes and subjective experiences of individuals with knee injuries or osteoarthritis, encompassing domains like pain, symptoms, activities of daily living, sports and recreation, and quality of life. [Knee Injury and Osteoarthritis Outcome Score The outcome measures will be evaluated at two distinct intervals: <br>1. Baseline (pre-intervention): These assessments are conducted before the intervention to establish the initial state of participants' knee osteoarthritis (KOA) condition. <br>2. Immediately post-completion of the intervention (short term, week-8): These measurements are taken immediately after the last intervention, occurring at week 8. <br>]

Secondary Outcome Measures