TO DETERMINE IF CARDIOVASCULAR RISK INDICES INCLUDING POSTPRANDIAL HYPERTRIGLYCERIDAEMIA ARE MODIFIED FAVOURABLY BY NICOTINIC ACID (NIACIN) IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME (PCOS)
- Conditions
- Polycystic ovary syndrome
- Registration Number
- EUCTR2009-015729-35-GB
- Lead Sponsor
- Hull and East Yorkshire Hospitals NHS Trust
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Age 18-50 year
Polycystic ovary syndrome (evidence of anovulation, clinical or biochemical hyperandrogenism, polycystic ovaries on ultrasound scanning which meets the PCOS diagnostic criteria of Rotterdam consensus statement)
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Pregnancy/ who is trying to conceive/Breast Feeding
2)History of cardiovascular, renal, hepatic and active thyroid disease
3)History of Gout
4)History of alcohol abuse
5)History of Diabetes
6)History of bleeding disorders/ active peptic ulcers
7)Patient on antihypertensive medications
8)Patient on anticoagulants
9)History of allergy to nicotinic acid/ laropiprant/food
10)Patient on any hormonal replacement or oral contraceptive pills or cholesterol lowering agents
11) History of smoking more than 15 pack year
12)Unwilling for GP to be informed
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method