NCT05342220已完成不适用
Effect of Ischemic Preconditioning on Relapse of Nonvalvular Atrial Fibrillation After Electrocardioversion
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 240
- 试验地点
- 1
- 主要终点
- Number of subjects with recurrence of atrial fibrillation 30 days after electrical cardioversion
研究概览
简要总结
Remote ischemic preconditioning is one way to influence the success of therapy in cardiovascular patients. By means of remote ischemic preconditioning the incidence of atrial fibrillation after cardiac surgery was reduced by 54%. The investigators aim to investigate the effect of ischemic preconditioning in an easy-to-perform protocol with regard to the recurrence of atrial fibrillation after electrical cardioversion.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with paroxysmal or persistent atrial fibrillation who give written informed consent to participate in the study
- •Age > 18 years
- •Consent capacity
排除标准
- •Age under 18 years
- •Pregnancy
- •Lack of consent capacity
研究组 & 干预措施
Control
Sham Comparator
Sham preconditioning
干预措施: Sham preconditioning (Procedure)
Remote Ischemic Preconditioning
Active Comparator
Remote ischemic preconditioining
干预措施: Remote ischemic preconditioning (Procedure)
结局指标
主要结局
Number of subjects with recurrence of atrial fibrillation 30 days after electrical cardioversion
时间窗: 30 days
次要结局
- Cumulative number of shocks delivered for successfull electrocardioversion(30 days)
- Minimum energy required for successful electrocardioversion (in Joule)(30 days)
- Cumulative energy applied for successfull electrocardioversion (in Joule)(30 days)
- Number of patients with short-term cardioversion success(30 seconds)
- Number of patients experiencing death from any cause, stroke /transient ischemic attack, relevant post-ECV arrhythmia and procedure-associated complications(30 days)
研究者
研究点 (1)
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