Microbiota profiling in pediatric inflammatory bowel disease by means of IS-pro
Completed
- Conditions
- chronic intestinal inflammationInflammatory bowel disease (IBD)10017969
- Registration Number
- NL-OMON37721
- Lead Sponsor
- Vrije Universiteit Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
- Age 17 years and below
- diagnosis of IBD (Crohn disease and ulcerative colitis) based on regular endoscopy, histology, intestinal MRI, video capsule endoscopy or a combination of these (IBD Working Group ESPGHAN, 2005)
Exclusion Criteria
- Proven infectious colitis during the last month as determined by positive stool culture for Salmonella, Shigella, Yersinia, Campylobacter, Clostridium toxins in stools or parasites in stools
- Use of antibiotics in the last 3 months prior to inclusion
- Use of probiotics in the last 3 months prior to inclusion
- Use of immunosuppressive therapy prior to the study
- Patients diagnosed with immunocompromised disease (any of various diseases that suppress the immune system)
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The fecal and mucosal samples will be analysed by means of IS-pro. The obtained<br /><br>intestinal microbiota profiles of the participants will subsequently be<br /><br>analysed in order to get better insight in the composition of the intestinal<br /><br>microbiota of newly diagnosed IBD patients (see study-objectives)</p><br>
- Secondary Outcome Measures
Name Time Method <p>not applicable</p><br>