Cardiac Magnetic Resonance in Children With Muscular Dystrophy

Completed

• Conditions: Duchenne Muscular Dystrophy; Becker Muscular Dystrophy; Limb Girdle Muscular Dystrophy

• Registration Number: NCT01081080
• Lead Sponsor: Cooperative International Neuromuscular Research Group

Brief Summary

This protocol will exploit novel state of the art cardiovascular magnetic resonance techniques to examine important changes in the heart in children with muscular dystrophy. The purpose of this study is to compare cardiac magnetic resonance (CMR) with the collected cardiac outcome data obtained in protocol: PITT1109 - Cardiac Outcome Measures in Children with Muscular Dystrophy.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2010-03-04
• Study First Submitted QC: 2010-03-04
• Study First Posted: 2010-03-05
• Study Start: 2010-04
• Primary Completion: 2011-10
• Study Completion: 2011-10
• Status Verified: 2013-01
• Last Update Submitted: 2013-01-10
• Last Update Posted: 2013-01-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Participant enrolled in the CINRG study: PITT1109 - Cardiac Outcome Measures in Children with Muscular Dystrophy

Exclusion Criteria

• Pregnant woman (when uncertain, participants will undergo urine testing) or lactating women

• Decompensated congestive heart failure (unable to lie flat during CMR)

• Impaired renal excretory function (calculated Glomerular Filtration Rate less than 30mL/min)

• Contra-indications to Magnetic Resonance Imaging:

  • Cardiac pacemaker or implantable defibrillator
  • Cerebral aneurysm clip
  • Neural stimulator
  • Metallic ocular foreign body
  • Harrington-rod
  • Any implanted device (i.e. insulin pump, drug infusion device)
  • Claustrophobia
  • Metal shrapnel or bullet

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (2)

University of Pittsburgh; 🇺🇸 Pittsburgh, Pennsylvania, United States

Children's National Medical Center; 🇺🇸 Washington, District of Columbia, United States