A Comparative Study of Mammography and Ultrasound for Breast Cancer Screening and Early Diagnosis
试验速览
- 阶段
- 不适用
- 入组人数
- 6,000
- 试验地点
- 1
- 主要终点
- screening yield
研究概览
简要总结
Improving the early diagnosis of breast cancer can reduce mortality. With mammography as the main tool for screening early breast cancer, the characteristics of dense breast and young onset of disease in Chinese women lowers the efficiency. The aim of this prospective study was to compare which method, x-ray or ultrasound, is more appropriate for screening and early diagnosis of breast cancer in Chinese women.
详细描述
Breast cancer has become the most common malignancy in women. Improving the early diagnosis of breast cancer can reduce mortality. Mammography is recommended as the main tool for screening and early diagnosis of breast cancer in the guidelines of European and American countries. However, the characteristics of dense breast and young onset of disease in Chinese women make the screening and early diagnosis strategies of Western countries, which are mainly based on mammography, unsuitable for Chinese women. The aim of this prospective study was to compare which method, x-ray or ultrasound, is more appropriate for screening and early diagnosis of breast cancer in Chinese women.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 35 Years 至 70 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Informed consent, subjects 35-70 years old, asymptomatic, able to undergo ultrasound and x-ray
排除标准
- •Localized breast erythema and ulceration, pregnancy, lactation, after previous breast implantation, already pathologically definite breast cancer patients
结局指标
主要结局
screening yield
时间窗: 3 years
The sensitivity, specificity, positive predictive value, and negative predictive value of the screening methods.
次要结局
- cost-effectiveness(3 years)