Lactobacillus Plantarum TCI999 in the Efficacy Verification Program of Hair and Body Health Care
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- The change of hair loss amount
研究概览
简要总结
To assess TCI999 on hair and body health care
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy adults aged above 20 years old
排除标准
- •Subject who is not willing to participate in this study.
- •Patients with diseases of the skin, liver, kidney.
- •Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder.
- •Female who is pregnant or nursing or planning to become pregnant during the course of the study.
- •The students taught by the PI.
- •Subjects who have wounds on the scalp and subjects who have used drugs to treat the scalp, received hair transplants or other scalp treatments within six months
研究组 & 干预措施
Placebo sachet
干预措施: Placebo sachet (Dietary Supplement)
TCI999 probiotic sachet
干预措施: TCI999 probiotic sachet (Dietary Supplement)
结局指标
主要结局
The change of hair loss amount
时间窗: Change from Baseline hair loss amount at 12 weeks
Collected and measured the weight of loss hair
The change of hair density
时间窗: Change from Baseline hair density at 12 weeks
Take a picture and observe the hair density
The change of intestinal microbiota
时间窗: Change from Baseline intestinal microbiota at 12 weeks
To evaluate the intestinal microbiota of fecal samples
The change of hair follicle strength
时间窗: Change from Baseline hair follicle strength at 12 weeks
Pull up the hair of the frontal bone, temporal bone and occipital bone (approximately 60 hairs/area) to assess the number of hair loss in each area
次要结局
- The change of testosterone of blood(Change from Baseline testosterone at 12 weeks)
- The change of scalp health(Change from Baseline scalp health at 12 weeks)
- The change of AR gene expression of blood(Change from Baseline AR gene expression at 12 weeks)
- The change of dihydrotestosterone of blood(Change from Baseline hair diameter at 12 weeks)
- The change of SRD5A1 gene expression of blood(Change from Baseline SRD5A1 gene expression at 12 weeks)
- The change of scalp gloss(Change from Baseline scalp gloss at 12 weeks)
- The change of scalp redness(Change from Baseline scalp redness at 12 weeks)
- The change of hair diameter(Change from Baseline hair diameter at 12 weeks)
- The change of TGF-β gene expression of blood(Change from Baseline TGF-β gene expression at 12 weeks)
- The change of IGF-1 gene expression of blood(Change from Baseline IGF-1 gene expression at 12 weeks)