Effect of Turmeric on Pruritus in Hemodialysis Patients

Early Phase 1

Completed

• Conditions: End Stage Renal Failure
• Interventions: Drug: turmeric; Drug: placebo

• Registration Number: NCT01037595
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

The purpose of this study is to see whether turmeric can be effective in treatment of pruritus in hemodialysis patients.

Detailed Description

pruritus is a common in hemodialysis patients and many treatment recommended for it . as turmeric has anti-inflammatory , anti-cytokine and anti-oxidant effect it may effective in treatment of uremic pruritus. thus we compared turmeric with placebo in this study

Study Timeline

• Study First Submitted: 2009-12-22
• Study First Submitted QC: 2009-12-22
• Study First Posted: 2009-12-23
• Study Start: 2010-09
• Primary Completion: 2010-10
• Study Completion: 2010-12
• Status Verified: 2013-05
• Last Update Submitted: 2013-05-12
• Last Update Posted: 2013-05-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Hemodialysis for more than 3 months
• More than 18 years old
• Pruritus

Exclusion Criteria

• Use other treatment for pruritus

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
turmeric	turmeric	turmeric 500 mg tid orally for 8 weeks
plasebo	placebo	placebo tid orally for 8 weeks

Primary Outcome Measures

Name	Time	Method
improvement in pruritus	6 mo

Trial Locations

Locations (1)

Shiraz University Hemodialysis Center; 🇮🇷 Shiraz, Fars, Iran, Islamic Republic of