Evaluation of chaturangula dala pralepa with and without panchnimba churna in eka kushtha(psoriasis)
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- improvement in following signs and symptoms of Eka-Kushtha (Psoriasis):
研究概览
简要总结
Psoriasis is an autoimmune, chronic inflammatory skin disorder clinically characterized by erythematous, sharply demarcated papules & rounded plaques, covered by silvery micaceous scales. Skin lesions of psoriasis are variably pruritic. It is chronic and is well known for its course of remissions and exacerbations. The effect of Shodhana Chikitsa can be increased if it is followed by Shamana Chikitsa which include both Antarparimarjan and Bahiparimarjan *Chikitsa.*In Charaka Samhita Eka Kushtha is described as Vata-Kaphaj diseases. It has sign & symptoms i.e. Aswedanam, Mahavastu and Matsyashakalopamam, which can be compared with symptoms of Psoriasis.The worldwide burden of Psoriasis is 2%, and the prevalence of Psoriasis in India ranges from 0.44% - 2.8%. Chaturangula dala pralepa decreases the mitotic activity of skin leading to reduced skin flaking. Panchnimba churna is tikta rasa pradhana which works excellently in skin disorders.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient having sign and symptoms of Eka-Kushtha.
- •Patient of age between 20-60 years.
- •Positive sign of psoriasis like Auspitz sign, Candle grease sign, etc.
- •Chronicity less than 5 yrs.
排除标准
- •Known case of Malignancy, IHD, CHF, and any other vascular disease.
- •Uncontrolled Diabetes Mellitus, and Hypertension & other life threatening and Complicated diseases.
- •Pregnant and lactating women.
- •Any other co-existing skin diseases.
- •Chronicity more than 5yrs.
结局指标
主要结局
improvement in following signs and symptoms of Eka-Kushtha (Psoriasis):
时间窗: 12 weeks
1. Aswednam
时间窗: 12 weeks
2. Mahavastu
时间窗: 12 weeks
3. Matsyashaklopam
时间窗: 12 weeks
4. Rukshta
时间窗: 12 weeks
5. Kandu
时间窗: 12 weeks
6. Auspitz sign
时间窗: 12 weeks
7. Candle grease sign
时间窗: 12 weeks
次要结局
- done on the basis of changes in clinical findings, relevant laboratory parameters and PASI score before during and at the end of trial.(12 weeks)
研究者
Dr Sanjay Kumar Tripathi
Rishikul Campus, Uttarakhand Ayurved University, Haridwar