Prophylactic effect of oral Tranexamic Acid on bleeding in knee replacement surgery

Islamic Azad University0 个研究点目标入组 30 人开始时间: 待定最近更新: 2019年4月23日

适应症

试验速览

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•The patient's full conditions for participation in the study and signature of the prepared form of the informed consent
•A person with a history of specific disease, such as kidney disease, liver disease, history of ischemia, heart, hypertension, history of self-sacrifice and signs of disability in the diagnosis and treatment of disability.
•Patients do not use aspirin or any other anticoagulants from the week before surgery: Plavix, heparin, enoxaparin, and warfarin.
•Do not observe a specific diet (it's not just herbivorous or meat-eaters, or the use of certain substances that lower blood glucose levels)
•Do not use special medication such as iron or other medications associated with bleeding.

•Patient dissatisfaction to continue participation
•Patients with abnormal clotting parameters (PT, PTT, BT, INR, platelet)
•People with high systolic blood pressure (185 in surgery day)
•During surgery and up to 6 hours after the operation, the osmotic arterial pressure is more than 20%.
•Patients with complications such as nausea and vomiting, color blindness, headache and dizziness, thromboemboli, myocardial ischemia and nutritional ischemia before and after surgery.

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