A Prospective Observational Study to Comparing Postoperative Pulmonary Complications in Patients Undergoing Off-Pump CABG Vs Minimally Invasive Off-Pump CABG.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 126
- 试验地点
- 1
- 主要终点
- Incidence and severity of postoperative pulmonary complications assessed using composite scoring, including Postoperative Atelectasis Severity Score, CURB-65 Severity Score, Ventilator Dependence Severity Score, Pleural Effusion Severity Score, and Asthma Severity Score (adapted for Bronchospasm), in patients undergoing Off-Pump CABG and Minimally Invasive Off-Pump CABG.
研究概览
简要总结
Coronary artery bypass grafting is a standard surgical procedure for the management of coronary artery disease. Conventional off pump coronary artery bypass grafting performed through median sternotomy may be associated with postoperative pulmonary complications such as atelectasis, pneumonia, pleural effusion,. and respiratory failure. Minimally invasive off pump coronary artery bypass grafting performed through a small thoracotomy avoids sternotomy and may reduce postoperative pulmonary complications by improving respiratory mechanics and lowering systemic inflammatory response.
This prospective observational comparative study aims to compare the incidence of postoperative pulmonary complications between patients undergoing off pump coronary artery bypass grafting and those undergoing minimally invasive off pump CABG. Postoperative pulmonary complications will be evaluated using validate scoring systems including the postoperative atelectasis severity score, CURB sixty five severity score, ventilator dependence severity score, pleural effusion severity score, and asthma severity score adapted for bronchospasm.
Given the significant impact of postoperative pulmonary complications on patient outcomes and health care costs, this study seeks to provide evidence on whether minimally invasive off pump CABG offers superior pulmonary outcomes, thereby guiding surgical decisions making in patients undergoing coronary revascularization.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Scheduled for elective off-pump CABG with general anesthesia, invasive mechanical ventilation, conventional median sternotomy or minimally invasive thoracotomy.
排除标准
- •1.Patients were excluded in case of emergent or redo surgeries 2.Patients with history of COPD.
- •3.Patients with known pulmonary Hypertension 4.Patients with EF less than forty five percentage in Echocardiography 5.Patients with significant history of smoking addiction 6.Body mass index greater than thirty five kilograms per square meter 7.Patient Refusal.
结局指标
主要结局
Incidence and severity of postoperative pulmonary complications assessed using composite scoring, including Postoperative Atelectasis Severity Score, CURB-65 Severity Score, Ventilator Dependence Severity Score, Pleural Effusion Severity Score, and Asthma Severity Score (adapted for Bronchospasm), in patients undergoing Off-Pump CABG and Minimally Invasive Off-Pump CABG.
时间窗: Assessed at twenty four, forty eight and seventy two hours.
次要结局
- Time of extubation from completion of surgery,(Need for re-intubation,)
研究者
ST ARISH
Department of Cardiac Anesthesiology,Sri Ramachandra Institute of Higher Education and Research, No. 1, Ramachandra Nagar, Porur, Chennai – 600 116.