The Additional effects of the Topical Application of Tranexamic Acid in on-pump cardiac surgery : a Double-blinded, Prospective, Randomized Controlled Trial
Not Applicable
Completed
- Conditions
- tranexamic acidpostoperative bleedingcardiopulmonary bypasscardiac surgerytranexamic acidpostoperative bleedingcardiopulmonary bypasscardiac surgery
- Registration Number
- TCTR20151210002
- Lead Sponsor
- Maharaj Nakorn Chiang Mai Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Open-heart operation under cardiopulmonary bypass
Age > 15 years
Exclusion Criteria
Re-do operation
Emergency case
Bleeding diathesis (hemophilia or platelet count < 100 x 109 /L)
Renal failure (creatinine level > 2.0 mg/dL)
Tranexamic acid allergy
Stop Aspirin, Clopidogrel < 7 days
Heparin administration within 24 hr
Reoperation from obvious surgical bleeding cause
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 24-hour chest tube blood loss 24 hour milliliter of blood loss via drainage tube
- Secondary Outcome Measures
Name Time Method Amount of RBC transfusion until discharge from hospital unit of blood,Re-exploration rate until discharge patient need to re-explore for stop bleeding or not.,Length of hospital stay until discharge from hospital number of day unitl patient was discharge from hospital,Mortality and morbidity until discharge from hospital number of dead and any significant complications after surgery,Tranexamic acid complications until discharge from hospital complications from treatment