NCT03162315已完成不适用
The Value of Progesterone for the Timing of the Embryo Transfer in IVF/ICSI: a Prospective Randomised Trial
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Clinical pregnancy rate
研究概览
简要总结
At the start of the controlled ovarian stimulation as a part of the IVF/ICSI treatment patients are informed about this trial. In case they gave informed consent and they have a progesterone level between 1 and 1.5 ng/ml at the day of the hCG injection, they will be randomised. One group of patients will have a fresh embryo transfer, in the second group all embryos will be cryopreserved and transfered in a subsequent (natural or artificial) cycle. The aim of this study is to compare clinical pregnancy rate between the two groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •IVF/ICSI treatment
- •progesterone > 1 ng/ml and ≤ 1.5 ng/ml
排除标准
- •> 40 years
- •AMH ≤ 1 ng/ml
- •Conditions influencing pregnancy rate (e.g. hydrosalphinx, uterus malformation, hyperprolactinemia and other endocrine conditions; with the exception of controlled thyroid function disease)
- •no available progesterone value on the day of hCG-injection
研究组 & 干预措施
Fresh embryo transfer
No Intervention
fresh embryo transfer (standard of care)
Freeze all
Experimental
Vitrification of all embryos and replacement of a thawed embryo in a subsequent cycle
干预措施: Freeze all (Procedure)
结局指标
主要结局
Clinical pregnancy rate
时间窗: 7 gestational weeks
次要结局
- Ongoing pregnancy rate(25 gestational weeks)
- Live birth rate(Delivery)
研究者
研究点 (1)
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