The Value of Progesterone for the Timing of the Embryo Transfer in IVF/ICSI: a Prospective Randomised Trial
Not Applicable
Completed
- Conditions
- Clinical Pregnancy Rate
- Interventions
- Procedure: Freeze all
- Registration Number
- NCT03162315
- Lead Sponsor
- University Hospital, Ghent
- Brief Summary
At the start of the controlled ovarian stimulation as a part of the IVF/ICSI treatment patients are informed about this trial. In case they gave informed consent and they have a progesterone level between 1 and 1.5 ng/ml at the day of the hCG injection, they will be randomised. One group of patients will have a fresh embryo transfer, in the second group all embryos will be cryopreserved and transfered in a subsequent (natural or artificial) cycle. The aim of this study is to compare clinical pregnancy rate between the two groups.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 24
Inclusion Criteria
- IVF/ICSI treatment
- progesterone > 1 ng/ml and ≤ 1.5 ng/ml
Exclusion Criteria
- > 40 years
- AMH ≤ 1 ng/ml
- Conditions influencing pregnancy rate (e.g. hydrosalphinx, uterus malformation, hyperprolactinemia and other endocrine conditions; with the exception of controlled thyroid function disease)
- no available progesterone value on the day of hCG-injection
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Freeze all Freeze all Vitrification of all embryos and replacement of a thawed embryo in a subsequent cycle
- Primary Outcome Measures
Name Time Method Clinical pregnancy rate 7 gestational weeks
- Secondary Outcome Measures
Name Time Method Ongoing pregnancy rate 25 gestational weeks Live birth rate Delivery
Trial Locations
- Locations (1)
Ghent University Hospital - Department of Reproductive Medicine
🇧🇪Ghent, Belgium