Respiratory Muscle Strength in Patients With Idiopathic Pulmonary Fibrosis: The Relationship With Exercise Capacity, Physical Activity Level, and Quality of Life
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Idiopathic Pulmonary Fibrosis
- Sponsor
- Istanbul Medipol University Hospital
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- The Quality of Life Questionaire
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Respiratory muscle strength, dyspnea perception, physical activity and quality of life measurements will be performed and groups will be compared in two groups consisting of patients with idiopathic pulmonary fibrosis referred to pulmonary rehabilitation clinic and healthy volunteers in similar age range.
Detailed Description
The patients who have agreed to participate in the study from patients diagnosed with idiopathic pulmonary fibrosis referred to the center of pulmonary rehabilitation from the interstitial lung disease polyclinic will be included in the study. In addition, a healthy adult control group will be established from similar age groups. The two groups will be compared in terms of outcome measures.The study outcome measurements are maximum inspiratory/expiratory muscle strength , international physical activity questionaire, modified Medical Research Council dyspnea scale, Short form 36 quality of lide questionaire, fatigue severity scale, six minute walking test.
Investigators
esra pehlivan
Principal investigator
Istanbul Medipol University Hospital
Eligibility Criteria
Inclusion Criteria
- •Between the ages of 18-70
- •Patients signing informed consent form
- •Patients diagnosed with idiopathic pulmonary fibrosis.
Exclusion Criteria
- •Patients who use steroids for less than 1 year
- •The patient does not want to participate in the study
Outcomes
Primary Outcomes
The Quality of Life Questionaire
Time Frame: 20 minutes
Short Form 36
Maximum inspiratory muscle pressure
Time Frame: 15 minutes
The mouth pressure measurement was performed with the Micro-RPM® instrument from SensorMEDIC. Patient placed a rubber mouthpiece with flanges, on the device, sealed their lips firmly around the mouthpiece, exhaled/inhaled slowly and completely, and then tried to breath in as hard as possible. The patient was allowed to rest for about a minute and the maneuver was repeated five times. Verbal or visual feedback was provided after each maneuver. The aim is that the variability between measurements is less than 10 cm H2O. The maximum value was obtained.
Maximum expiratory muscle pressure
Time Frame: 15 minutes
The mouth pressure measurement was performed with the Micro-RPM® instrument from SensorMEDIC. Patient placed a rubber mouthpiece with flanges, on the device, sealed their lips firmly around the mouthpiece, exhaled/inhaled slowly and completely, and then tried to breath in as hard as possible. The patient was allowed to rest for about a minute and the maneuver was repeated five times. Verbal or visual feedback was provided after each maneuver. The aim is that the variability between measurements is less than 10 cm H2O. The maximum value was obtained.
The distance covered in six-minute walk test
Time Frame: 10 minutes
The test was conducted in a 30-meter corridor in line with American Thoracic Society (ATS) guidelines. Patients were told that they should walk as fast as they can walk. Before and after the test, oxygen saturation, heart rate, Borg fatigue rating, and walking distance were recorded.
International Physical Activity Questionnaire
Time Frame: 15 minutes
The International Physical Activity Questionnaire (IPAQ) was developed as an instrument for cross-national monitoring of physical activity and inactivity. This measure assesses the types of intensity of physical activity and sitting time that people do as part of their daily lives are considered to estimate total physical activity in MET-min/week and time spent sitting.
Secondary Outcomes
- The modified Medical Research Council (mMRC) scale(3 minutes)
- The fatigue severity scale(15 minutes)