MedPath

effect of olive leaf extract on Covid-19 patients

Phase 2
Conditions
COVID - 19.
B34.2
Coronavirus infection, unspecified
Registration Number
IRCT20201128049520N1
Lead Sponsor
Khoram-Abad University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
129
Inclusion Criteria

All patients with Quid-19 based on standard diagnostic test (positive PCR test, CT scan of lung) approved by infectious disease specialist
Age range is 18 to 70 years
Have a level of consciousness of 15 according to the Glasgow standard

Exclusion Criteria

Take oleopurine supplements 3 months before the study
Use of mechanical ventilation equipment
Existence of underlying respiratory diseases such as COPD, asthma
Taking anti-hypertensive, anti-platelet and anti-diabetic drugs
Pregnancy and lactation
Immune system deficiency or the use of immunosuppressive drugs
Malignancies
Presence of heart, kidney, liver, blood pressure, diabetes and corticosteroid disorders
Reluctance to continue cooperation
The patient is discharged earlier than the completion of the treatment period
Hypotension (mean arterial pressure less than 70 mm Hg)
Hypoglycemia (blood sugar less than 75 mg / dL)
Existence of allergies to drugs before and during the study
Lack of proper use of drugs
The need for therapeutic interventions other than the usual therapeutic interventions during research such as the need for dialysis, angioplasty and ...
Participate in other research that in any way affects the results of the research

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Arterial oxygen saturation. Timepoint: Before starting the intervention, then for five days twice a day from 6 am to 6 pm. Method of measurement: Medair pulse oximeter device.;Heart rate. Timepoint: Before starting the intervention, then for five days twice a day from 6 am to 6 pm. Method of measurement: pulse oximeter device.;Temperatures. Timepoint: Before starting the intervention, then for five days twice a day from 6 am to 6 pm. Method of measurement: Digital thermometer.;Blood pressure. Timepoint: Before starting the intervention, then for five days twice a day from 6 am to 6 pm. Method of measurement: Hand pressure gauge.;Complete blood count. Timepoint: Before and during the intervention on a daily basis. Method of measurement: Patient file.
Secondary Outcome Measures
NameTimeMethod
Severity of general symptoms of Covid-19 disease. Timepoint: Before and during the intervention on a daily basis. Method of measurement: Symptom Severity Questionnaire.;Duration of hospitalization. Timepoint: Patient discharge time. Method of measurement: Counting the number of days the patient is hospitalized.
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