Serum Maresin-1 Predicts the Severity of Severe Acute Pancreatitis

• Conditions: Pancreatitis, Acute

• Registration Number: NCT03364920
• Lead Sponsor: Weiqin Li

Brief Summary

This is a retrospective study about serum Maresin-1 level in different severe acute pancreatitis patients. The investigators want to study the correlation between the level of serum Maresin-1 and the severity of SAP, of course the clinical outcomes. The investigators want to find some biomarkers and strategy target drugs of severe acute pancreatitis.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-11-23
• Status Verified: 2017-12
• Study First Submitted QC: 2017-12-06
• Last Update Submitted: 2017-12-06
• Study First Posted: 2017-12-07
• Last Update Posted: 2017-12-07
• Study Start: 2018-01-01
• Primary Completion: 2019-01-01
• Study Completion: 2020-01-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Clinical diagnosis of Severe Acute Pancreatitis
• Biliary pancreatitis
• 7 days of the onset

Exclusion Criteria

• Surgical patients
• Serious diseases and infection
• Alcoholic pancreatitis
• Hypertriglyceridemia pancreatitis
• Disorder of Glucolipide Metabolism：diabetes mellitus, hypertriglyceridemia, BMI>30

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
mortality	up to 28 days	The level of serum maresin-1 predicts the severity of severe acute pancreatitis

Secondary Outcome Measures

Name	Time	Method
The incidence of MODS	through study completion, an average of 1 year	The level of serum maresin-1 predicts the severity of severe acute pancreatitis
The incidence of IPN	through study completion, an average of 1 year	The level of serum maresin-1 predicts the severity of severe acute pancreatitis