NCT03590275已完成不适用
Observational Retrospective Study of Evaluation of Prognostic Factors in Advanced Pancreatic Cancer Patients Treated With FOLFIRINOX
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 343
- 试验地点
- 7
- 主要终点
- Overall survival
研究概览
简要总结
The aim of this study is to identify new prognostic factors in patients affected by advanced pancreatic carcinoma treated with first line chemotherapy with FOLFIRINOX regimen. Primary objective is the identification of clinical, laboratory and pathologic factors affecting overall survival of these patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age >18 years
- •citologically or histologically confirmed pancreatic carcinoma
- •disease stage III or IV according to the American Joint Committee on Cancer (AJCC) staging system
- •access to clinical informations collected before first-line starting
- •availability of objective response evaluation and survival data
- •written informed consent
排除标准
- •diagnosis of other neoplasia than pancreatic carcinoma
- •treatment with drugs other than FOLFIRINOX
- •treatment with experimental drugs in combination with FOLFIRINOX
- •unavailability of clinical and pathological data
结局指标
主要结局
Overall survival
时间窗: up to 2 years
Overall survival is defined as the time from study entry until death from any cause. Patients who are alive at the end of the study will be censored at that point.
次要结局
- Progression-free survival(up to 2 years)
- Response rate(up to 2 years)
- Toxicity rate(up to 2 years)
研究者
Alfredo Falcone
Prof. Alfredo Falcone
Azienda Ospedaliero, Universitaria Pisana
研究点 (7)
Loading locations...
相似试验
已完成
不适用
A Longitudinal, Observational Biomarker Study in Pancreatic Cancer Patients Receiving ChemotherapyPancreatic CancerNCT04281511National Cancer Center, Korea238
进行中（未招募）
不适用
Endocrine and Exocrine Secretory Function Alterations After Moderately Severe and Severe Acute PancreatitisAcute Pancreatitis (AP)Diabetes MellitusNCT06590935Shanghai Changzheng Hospital120
撤回
不适用
Post Pancreatitis Complications Study (Based on a Prospective Data Base)PancreatitisNCT03284489Nantes University Hospital
尚未招募
不适用
Prognostic Biomarkers of Pancreatic Cancer Based on Proteomic TechniquesProteomicsPrognostic BiomarkersPancreatic CancerNCT05289895The Affiliated Hospital of Qingdao University220
Unknown
不适用
Prognostic Biomarkers of Pancreatic Cancer Based on Proteomics TechniquesPatientsNCT05088161The Affiliated Hospital of Qingdao University20